Frontiers in Medicine (Jun 2021)

Understanding Immune Thrombocytopenia: Looking Out of the Box

  • Alexandra Schifferli,
  • Alexandra Schifferli,
  • Franco Cavalli,
  • Bertrand Godeau,
  • Howard A. Liebman,
  • Mike Recher,
  • Paul Imbach,
  • Thomas Kühne,
  • Thomas Kühne

DOI
https://doi.org/10.3389/fmed.2021.613192
Journal volume & issue
Vol. 8

Abstract

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The pathogenesis of immune thrombocytopenia (ITP) is increasingly being elucidated, and its etiology is becoming more frequently identified, leading to a diagnostic shift from primary to secondary ITP. The overlap between autoimmunity, immunodeficiency, and cancer is evident, implying more interdisciplinarity in daily care. This mini-review is based on an expert meeting on ITP organized by the Intercontinental Cooperative ITP Study Group and presents the challenges of hematologists in understanding and investigating “out of the box” concepts associated with ITP.

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