A Phaeohyphomycosis Case: A Rare Entity

Abstract

Phaeohyphomycosis is the term used to describe infections with darkly pigmented moulds appearing as septate filaments in host tissues. The disease is a histopathological rather than a clinical entity. A 79-year-old patient presented with multiple ulcerated lesions and nodules on the face. Microbiological culture identified the fungal isolate as phaeohyphomycosis. In the histopathological examination, granuloma formation with neutrophils in the center was detected due to infection. Oral daily 400 mg itraconazole was administered for 6 months. Follow-up at 12 months demonstrated no signs of infection. Clinical manifestations of cutaneous phaeohyphomycosis vary significantly. Although optimal treatment options remain contraversial, this case of phaeohyphomycosis was successfully treated by itraconazole monotherapy.

Keywords

• phaeohyphomycosis
• black mould
• itraconazole