F1000Research (Feb 2024)

Turmeric extract gel and honey in post-cesarean section wound healing: A preliminary study [version 2; peer review: 2 approved, 1 approved with reservations]

  • Agriyaningsih Oktaviana,
  • Zafitri Nulandari,
  • Risfah Yulianti,
  • Melani Kamsurya,
  • Andi Nilawati Usman,
  • Sartini Sartini,
  • Dinah Inrawati Agustin,
  • Fendi Fendi

Journal volume & issue
Vol. 12

Abstract

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Background Delivery by cesarean section (SC) increases the risk of a surgical site infection (SSI). Therapy from health services and complementary therapy reduce the risk of infection and accelerate the wound-healing process. This study compared wound healing after SC with a turmeric extract gel and original Trigona honey. Methods Female white rats (Rattus novergicus) with pre- and post-testing and a control group were included in this experiment, which was conducted in June-July 2022. The test animals were 56 female white rats, 2-4 months old, weighing 150–350 g. The treatment group was divided into three subgroups with application of 50% and 75% turmeric extract gel and Trigona honey. The turmeric was given twice daily, and the honey was divided into two applications of twice a day and once a day. Wounds were assessed using the Reeda Scale. Results The fastest wound healing occurred in the group given Trigona honey twice daily. Redness, ecchymosis, and edema disappeared in this group on day 9 (score 0), and granulation tissue formed on day 9. The group that was administered 50% and 75% turmeric gel extract and Trigona honey once a day healed by days 12 and 15, respectively; all three of these interventions were better than the control group. Conclusions Administering Trigona honey twice daily was more effective for accelerating wound healing than the 50% or 75% turmeric extract gel. Original Trigona honey has the potential to be a post-SC wound healing agent.

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