CHIMIA (Nov 2011)
Chemical Biology Approaches to Membrane Homeostasis and Function
- Miwa Takahashi-Umebayashi,
- Kai Johnsson,
- Luc Reymond,
- Aurélien Roux,
- Robbie Loewith,
- Gerardo Turcatti,
- Christian Heinis,
- Stefan Matile,
- David Alonso Doval,
- Andreas Zumbuehl,
- Thomas Hannich,
- Ludovic Pineau,
- Howard Riezman
Affiliations
- Miwa Takahashi-Umebayashi
- Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
- Kai Johnsson
- Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
- Luc Reymond
- Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
- Aurélien Roux
- Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
- Robbie Loewith
- Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
- Gerardo Turcatti
- Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
- Christian Heinis
- Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
- Stefan Matile
- Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
- David Alonso Doval
- Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
- Andreas Zumbuehl
- Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
- Thomas Hannich
- Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
- Ludovic Pineau
- Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
- Howard Riezman
- Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland. [email protected]
- DOI
- https://doi.org/10.2533/chimia.2011.849
- Journal volume & issue
-
Vol. 65,
no. 11
Abstract
The study of membranes is at a turning point. New theories about membrane structure and function have recently been proposed, however, new technologies, combining chemical, physical, and biochemical approaches are necessary to test these hypotheses. In particular, the NCCR in chemical biology aims to visualize and characterize membrane microdomains and determine their function during hormone signaling.
Keywords
- Chemical biology
- Fluorescent dyes
- Giant unilamellar vesicles
- Insulin receptor
- Membranes
- Microdomains
