PLoS ONE (Jan 2023)

A pilot exploratory study examining the potential influence of continuous positive airway pressure devices on cranial molding trajectories in preterm infants.

  • Dana B McCarty,
  • Ashley Hite,
  • Anna Brown,
  • Kerry Blazek,
  • Lauren Quinn,
  • Sara Hammond,
  • Marcella Boynton,
  • T Michael O'Shea

DOI
https://doi.org/10.1371/journal.pone.0292671
Journal volume & issue
Vol. 18, no. 10
p. e0292671

Abstract

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ObjectiveThe objective of this exploratory study was to assess the potential impacts of two different continuous positive airway pressure (CPAP) devices on preterm infant head shape and circumference.Study designTwenty infants born at ResultsAt baseline, average total birthweight of infants was 1021 grams (SD = 227 grams), average gestational age was 26.9 weeks (SD = 1.80), mean CI was 79.7 cm (SD = 5.95), and HC was 10.2 cm (SD = 0.92). Days on CPAP ranged from 16 to 63 days, with an average of 40.7 (SD = 13.6) days. Neither CI nor HC differed by device type; however, the Fisher-Paykel device was associated with slightly greater HC growth rate.ConclusionCPAP devices and the pressures they apply plausibly contribute to preterm infant cranial molding over time, with the greatest potential impact on infants who require CPAP support for longer periods; however, these findings must be validated in larger cohorts. Additionally, positioning practices should be further examined to determine how they may contribute to or prevent the development of cranial molding deformity.