PLoS ONE (Jan 2021)

Predictors of severity and mortality among patients hospitalized with COVID-19 in Rhode Island.

  • Aakriti Pandita,
  • Fizza S Gillani,
  • Yiyun Shi,
  • Anna Hardesty,
  • Meghan McCarthy,
  • Jad Aridi,
  • Dimitrios Farmakiotis,
  • Silvia S Chiang,
  • Curt G Beckwith

DOI
https://doi.org/10.1371/journal.pone.0252411
Journal volume & issue
Vol. 16, no. 6
p. e0252411

Abstract

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BackgroundIn order for healthcare systems to prepare for future waves of COVID-19, an in-depth understanding of clinical predictors is essential for efficient triage of hospitalized patients.MethodsWe performed a retrospective cohort study of 259 patients admitted to our hospitals in Rhode Island to examine differences in baseline characteristics (demographics and comorbidities) as well as presenting symptoms, signs, labs, and imaging findings that predicted disease progression and in-hospital mortality.ResultsPatients with severe COVID-19 were more likely to be older (p = 0.02), Black (47.2% vs. 32.0%, p = 0.04), admitted from a nursing facility (33.0% vs. 17.9%, p = 0.006), have diabetes (53.9% vs. 30.4%, pConclusionsCertain patient characteristics and clinical features can help clinicians with early identification and triage of high-risk patients during subsequent waves of COVID-19.