Can dynamic imaging, using 18F-FDG PET/CT and CT perfusion differentiate between benign and malignant pulmonary nodules?

Marin Aleksander; Murchison John T.; Skwarski Kristopher M.; Tavares Adriana A.S.; Fletcher Alison; Wallace William A.; Salapura Vladka; van Beek Edwin J.R.; Mirsadraee Saeed

doi:10.2478/raon-2021-0024

Radiology and Oncology (May 2021)

Can dynamic imaging, using 18F-FDG PET/CT and CT perfusion differentiate between benign and malignant pulmonary nodules?

Marin Aleksander,
Murchison John T.,
Skwarski Kristopher M.,
Tavares Adriana A.S.,
Fletcher Alison,
Wallace William A.,
Salapura Vladka,
van Beek Edwin J.R.,
Mirsadraee Saeed

Affiliations

Marin Aleksander: Edinburgh Imaging facility Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Murchison John T.: Department of Radiology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom
Skwarski Kristopher M.: Department of Respiratory Medicine, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom
Tavares Adriana A.S.: Edinburgh Imaging facility Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Fletcher Alison: Edinburgh Imaging facility Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Wallace William A.: Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom
Salapura Vladka: Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
van Beek Edwin J.R.: Edinburgh Imaging facility Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Mirsadraee Saeed: Edinburgh Imaging facility Queens Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

DOI: https://doi.org/10.2478/raon-2021-0024
Journal volume & issue: Vol. 55, no. 3
pp. 259 – 267

Abstract

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The aim of the study was to derive and compare metabolic parameters relating to benign and malignant pulmonary nodules using dynamic 2-deoxy-2-[fluorine-18]fluoro-D-glucose (18F-FDG) PET/CT, and nodule perfusion parameters derived through perfusion computed tomography (CT).

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

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