Sustained enzymatic activity and flow in crowded protein droplets

Andrea Testa; Mirco Dindo; Aleksander A. Rebane; Babak Nasouri; Robert W. Style; Ramin Golestanian; Eric R. Dufresne; Paola Laurino

doi:10.1038/s41467-021-26532-0

Nature Communications (Nov 2021)

Sustained enzymatic activity and flow in crowded protein droplets

Andrea Testa,
Mirco Dindo,
Aleksander A. Rebane,
Babak Nasouri,
Robert W. Style,
Ramin Golestanian,
Eric R. Dufresne,
Paola Laurino

Affiliations

Andrea Testa: Department of Materials, ETH Zürich
Mirco Dindo: Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University
Aleksander A. Rebane: Department of Materials, ETH Zürich
Babak Nasouri: Max Planck Institute for Dynamics and Self-Organization (MPIDS)
Robert W. Style: Department of Materials, ETH Zürich
Ramin Golestanian: Max Planck Institute for Dynamics and Self-Organization (MPIDS)
Eric R. Dufresne: Department of Materials, ETH Zürich
Paola Laurino: Protein Engineering and Evolution Unit, Okinawa Institute of Science and Technology Graduate University

DOI: https://doi.org/10.1038/s41467-021-26532-0
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 8

Abstract

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Living cells can harvest environmental energy to drive chemical processes. Here the authors design a minimal artificial system that achieves steady states at similar metabolic densities to microorganisms.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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