Utility of American Thyroid Association Guidelines 2021 for management of anaplastic thyroid carcinoma in Indian setting

Abstract

Though the incidence of anaplastic thyroid cancer (ATC) is minimal amongst thyroid cancers, the outcomes have remained dismal. As significant advances have happened after the 2012 guidelines, American Thyroid Association (ATA)-is a leading body, has recently released updated evidence-based guidelines of ATC in 2021. A need to interpret this guideline in the Indian context was perceived. The 2021 ATC guidelines by ATA, with relevant literature, were reviewed. The recommendations for specific subcategories were compiled. Relevant information pertaining to the Indian scenario was discussed with specific subcategories with Indian evidence. Future direction observations were shared. ATA has provided practical and updated guidelines for ATC. There are some region-specific considerations in the implementation of recommendations. A well-organized research approach and resource allocation are required to optimize ATC management in India.

Keywords

• anaplastic thyroid cancer
• systemic therapy
• targeted therapy
• thyroidectomy