The Anticancer Potential of Quassinoids—A Mini-Review

Cai Lu; Si-Nan Lu; Di Di; Wei-Wei Tao; Lu Fan; Jin-Ao Duan; Ming Zhao; Chun-Tao Che

Engineering (Jul 2024)

The Anticancer Potential of Quassinoids—A Mini-Review

Cai Lu,
Si-Nan Lu,
Di Di,
Wei-Wei Tao,
Lu Fan,
Jin-Ao Duan,
Ming Zhao,
Chun-Tao Che

Affiliations

Cai Lu: Jiangsu Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China; National and Local Collaborative Engineering Center of Chinese Medicinal Resource Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
Si-Nan Lu: Jiangsu Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China; National and Local Collaborative Engineering Center of Chinese Medicinal Resource Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
Di Di: Jiangsu Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China; National and Local Collaborative Engineering Center of Chinese Medicinal Resource Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
Wei-Wei Tao: School of Chinese Medicine & School of Integrated Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
Lu Fan: School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
Jin-Ao Duan: Jiangsu Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China; National and Local Collaborative Engineering Center of Chinese Medicinal Resource Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
Ming Zhao: Jiangsu Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China; National and Local Collaborative Engineering Center of Chinese Medicinal Resource Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, IL 60612, USA; Corresponding authors.
Chun-Tao Che: Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, IL 60612, USA; Corresponding authors.

Journal volume & issue: Vol. 38
pp. 27 – 38

Abstract

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The anticancer potential of quassinoids has attracted a great deal of attention for decades, and scientific data revealing their possible applications in cancer management are continuously increasing in the literature. Aside from the potent cytotoxic and antitumor properties of these degraded triterpenes, several quassinoids have exhibited synergistic effects with anticancer drugs. This article provides an overview of the potential anticancer properties of quassinoids, including their cytotoxic and antitumor activities, mechanisms of action, safety evaluation, and potential benefits in combination with anticancer drugs.

Published in Engineering

ISSN: 2095-8099 (Print); 2096-0026 (Online)
Publisher: Elsevier
Country of publisher: China
LCC subjects: Technology: Engineering (General). Civil engineering (General)
Website: http://www.journals.elsevier.com/engineering

About the journal

Abstract

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