Matrix metalloproteinase 2 knockdown suppresses the proliferation of HepG2 and Huh7 cells and enhances the cisplatin effect

Liu Jiangwei; Li Xiaocheng; Huang Jianzhao; Liu Yan

doi:10.1515/med-2019-0039

Open Medicine (May 2019)

Matrix metalloproteinase 2 knockdown suppresses the proliferation of HepG2 and Huh7 cells and enhances the cisplatin effect

Liu Jiangwei,
Li Xiaocheng,
Huang Jianzhao,
Liu Yan

Affiliations

Liu Jiangwei: Department of Hepatobiliary Surgery, Guizhou Provincial People’s Hospital, No. 1 Baoshan South Road, Guizhou550002, China
Li Xiaocheng: Department of Hepatobiliary Surgery, Guizhou Provincial People’s Hospital, No. 1 Baoshan South Road, Guizhou550002, China
Huang Jianzhao: Department of Hepatobiliary Surgery, Guizhou Provincial People’s Hospital, No. 1 Baoshan South Road, Guizhou550002, China
Liu Yan: Department of Hepatobiliary Surgery, Guizhou Provincial People’s Hospital, No. 1 Baoshan South Road, Guizhou550002, China

DOI: https://doi.org/10.1515/med-2019-0039
Journal volume & issue: Vol. 14, no. 1
pp. 384 – 391

Abstract

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This study evaluated the functions of matrix metalloproteinase 2 (MMP2) in hepatocellular carcinoma (HCC) cells and assessed the effects of MMP2 on HCC cell sensitivity to cisplatin.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

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Abstract

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