Analysis of influencing factors of long⁃term prognosis after surgery for spontaneous cerebellar hemorrhage

Abstract

Objective To explore the influencing factors of long⁃term prognosis of patients with spontaneous cerebellar hemorrhage (SCH) after surgery. Methods Total 121 patients with SCH admitted to the Second Affiliated Hospital of Air Force Military Medical University from January 2012 to September 2019 were included. The prognosis was assessed by the modified Rankin Scale (mRS) 12 months after surgery, and the risk factors related to dismal prognosis were screened by univariate and multivariate Logistic regression analysis. Results The age (P=0.001), proportion of Glasgow Coma Scale (GCS) score≤8 (P=0.000), activated partial thromboplastin time (P=0.003), random blood glucose level (P=0.044) and ventilator assisted ventilation ratio (P=0.015) of patients with poor prognosis (mRS score 4-6, n=79) were higher than those of patients with good prognosis (mRS score 0-3, n=42), while platelet count was lower than those of patients with good prognosis (P=0.017). There was significant difference in surgery modes between 2 groups (P=0.001). Logistic regression analysis showed that older age (OR=1.090, 95%CI: 1.032-1.151; P=0.002), high serum D⁃dimer level (OR=1.339, 95%CI: 1.034-1.735; P=0.027), craniotomy hematoma removal (OR=4.949, 95%CI: 1.310-18.691; P=0.018) and hematoma puncture drainage (OR=6.789, 95%CI: 1.249-36.912; P=0.027) were the main risk factors for long⁃term dismal prognosis after surgery for SCH. Conclusions Older age, high serum D⁃dimer level and surgery modes are the risk factors for long⁃term dismal prognosis after surgery for SCH.

Keywords

• cerebral hemorrhage
• cerebellum
• neurosurgical procedures
• prognosis
• risk factors
• logistic models