Novel 5‑Substituted Oxindole Derivatives as Bruton’s Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation

• Vani Madhuri Velavalapalli,
• Venkatanarayana Chowdary Maddipati,
• Soňa Gurská,
• Narendran Annadurai,
• Barbora Lišková,
• Naresh Kumar Katari,
• Petr Džubák,
• Marián Hajdúch,
• Viswanath Das,
• Rambabu Gundla

Affiliations

Vani Madhuri Velavalapalli

GITAM School of Pharmacy, GITAM Deemed to Be University, Hyderabad, Telangana, India

Venkatanarayana Chowdary Maddipati

Department of Chemistry, GITAM School of Science, GITAM Deemed to Be University, Hyderabad, Telangana, India

Soňa Gurská

Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic

Narendran Annadurai

Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic

Barbora Lišková

Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic

Naresh Kumar Katari

Department of Chemistry, GITAM School of Science, GITAM Deemed to Be University, Hyderabad, Telangana, India

Petr Džubák

Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic

Marián Hajdúch

Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic

Viswanath Das

Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic

Rambabu Gundla

Department of Chemistry, GITAM School of Science, GITAM Deemed to Be University, Hyderabad, Telangana, India