Nature Communications (Nov 2020)

Quadruple C-H activation coupled to hydrofunctionalization and C-H silylation/borylation enabled by weakly coordinated palladium catalyst

  • Bo-Cheng Tang,
  • Wen-Xuan Lin,
  • Xiang-Long Chen,
  • Cai He,
  • Jin-Tian Ma,
  • Yan-Dong Wu,
  • Yu Lan,
  • An-Xin Wu

DOI
https://doi.org/10.1038/s41467-020-19508-z
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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Combining the Heck reaction with other transformations provides a powerful strategy to access diverse, complex compounds. Here, the authors report a weak coordination dominated Pd(0)-catalyzed quadruple C-H activation followed by hydro-functionalization, C-H silylation, and C-H borylation.