Water-mediated deracemization of a bisporphyrin helicate assisted by diastereoselective encapsulation of chiral guests

Naoki Ousaka; Shinya Yamamoto; Hiroki Iida; Takuya Iwata; Shingo Ito; Yuh Hijikata; Stephan Irle; Eiji Yashima

doi:10.1038/s41467-019-09443-z

Nature Communications (Mar 2019)

Water-mediated deracemization of a bisporphyrin helicate assisted by diastereoselective encapsulation of chiral guests

Naoki Ousaka,
Shinya Yamamoto,
Hiroki Iida,
Takuya Iwata,
Shingo Ito,
Yuh Hijikata,
Stephan Irle,
Eiji Yashima

Affiliations

Naoki Ousaka: Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University
Shinya Yamamoto: Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University
Hiroki Iida: Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University
Takuya Iwata: Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University
Shingo Ito: Department of Chemistry, Graduate School of Science, Nagoya University
Yuh Hijikata: Department of Chemistry, Graduate School of Science, Nagoya University
Stephan Irle: Department of Chemistry, Graduate School of Science, Nagoya University
Eiji Yashima: Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University

DOI: https://doi.org/10.1038/s41467-019-09443-z
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 11

Abstract

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Deracemization is a powerful method which allows transformation of racemic mixtures into excess enantiomer, but was applied only to small chiral molecular systems so far. Here the authors report deracemization of a kinetically stable bisporphyrin helicate upon encapsulation of chiral aromatic guests.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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