Ecotoxicology and Environmental Safety (Jul 2023)

Toxicity, formation, contamination, determination and mitigation of acrylamide in thermally processed plant-based foods and herbal medicines: A review

  • Min Fan,
  • Xiaoying Xu,
  • Wenjun Lang,
  • Wenjing Wang,
  • Xinyu Wang,
  • Angjun Xin,
  • Fangmei Zhou,
  • Zhishan Ding,
  • Xiaoqing Ye,
  • Bingqi Zhu

Journal volume & issue
Vol. 260
p. 115059

Abstract

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Thermal processing is one of the important techniques for most of the plant-based food and herb medicines before consumption and application in order to meet the specific requirement. The plant and herbs are rich in amino acids and reducing sugars, and thermal processing may lead to Maillard reaction, resulting as a high risk of acrylamide pollution. Acrylamide, an organic pollutant that can be absorbed by the body through the respiratory tract, digestive tract, skin and mucous membranes, has potential carcinogenicity, neurological, genetic, reproductive and developmental toxicity. Therefore, it is significant to conduct pollution determination and risk assessment for quality assurance and security of medication. This review demonstrates state-of-the-art research of acrylamide focusing on the toxicity, formation, contamination, determination, and mitigation in taking food and herb medicine, to provide reference for scientific processing and ensure the security of consumers.

Keywords