Nature Communications (Nov 2022)

Critical Offset Magnetic PArticle SpectroScopy for rapid and highly sensitive medical point-of-care diagnostics

  • Patrick Vogel,
  • Martin Andreas Rückert,
  • Bernhard Friedrich,
  • Rainer Tietze,
  • Stefan Lyer,
  • Thomas Kampf,
  • Thomas Hennig,
  • Lars Dölken,
  • Christoph Alexiou,
  • Volker Christian Behr

DOI
https://doi.org/10.1038/s41467-022-34941-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

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Sensitive methods for antibody detection tend to be expensive and slow. Here, the authors report a magnetic particle spectroscopy method named COMPASS, as a rapid and low-cost technique which is comparable to ELISA in terms of sensitivity but with a measurement times of seconds.