Nature Communications (Apr 2016)
Explosive cell lysis as a mechanism for the biogenesis of bacterial membrane vesicles and biofilms
- Lynne Turnbull,
- Masanori Toyofuku,
- Amelia L. Hynen,
- Masaharu Kurosawa,
- Gabriella Pessi,
- Nicola K. Petty,
- Sarah R. Osvath,
- Gerardo Cárcamo-Oyarce,
- Erin S. Gloag,
- Raz Shimoni,
- Ulrich Omasits,
- Satoshi Ito,
- Xinhui Yap,
- Leigh G. Monahan,
- Rosalia Cavaliere,
- Christian H. Ahrens,
- Ian G. Charles,
- Nobuhiko Nomura,
- Leo Eberl,
- Cynthia B. Whitchurch
Affiliations
- Lynne Turnbull
- The ithree institute, University of Technology Sydney
- Masanori Toyofuku
- Department of Life and Environmental Sciences, University of Tsukuba
- Amelia L. Hynen
- The ithree institute, University of Technology Sydney
- Masaharu Kurosawa
- Department of Life and Environmental Sciences, University of Tsukuba
- Gabriella Pessi
- Department of Plant and Microbial Biology, University of Zurich
- Nicola K. Petty
- The ithree institute, University of Technology Sydney
- Sarah R. Osvath
- The ithree institute, University of Technology Sydney
- Gerardo Cárcamo-Oyarce
- Department of Plant and Microbial Biology, University of Zurich
- Erin S. Gloag
- The ithree institute, University of Technology Sydney
- Raz Shimoni
- The ithree institute, University of Technology Sydney
- Ulrich Omasits
- Department of Biology, Institute of Molecular Systems Biology, ETH Zurich
- Satoshi Ito
- Department of Life and Environmental Sciences, University of Tsukuba
- Xinhui Yap
- The ithree institute, University of Technology Sydney
- Leigh G. Monahan
- The ithree institute, University of Technology Sydney
- Rosalia Cavaliere
- The ithree institute, University of Technology Sydney
- Christian H. Ahrens
- Agroscope, Institute for Plant Production Sciences, Research Group Molecular Diagnostics, Genomics and Bioinformatics, & Swiss Institute of Bioinformatics (SIB)
- Ian G. Charles
- The ithree institute, University of Technology Sydney
- Nobuhiko Nomura
- Department of Life and Environmental Sciences, University of Tsukuba
- Leo Eberl
- Department of Plant and Microbial Biology, University of Zurich
- Cynthia B. Whitchurch
- The ithree institute, University of Technology Sydney
- DOI
- https://doi.org/10.1038/ncomms11220
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 13
Abstract
Many bacteria release DNA and membrane vesicles through unclear mechanisms. Here, the authors show that a prophage endolysin is involved in the explosive lysis of a sub-population of cells in Pseudomonas aeruginosa, releasing cytoplasmic content and membrane fragments that rapidly form membrane vesicles.
