Química Nova (Jan 2008)

Validação de métodos cromatográficos para a determinação de resíduos de medicamentos veterinários em alimentos Validation of chromatographic methods for the determination of residues of veterinary drugs in foods

  • Jonas Augusto Rizzato Paschoal,
  • Susanne Rath,
  • Flavia Pereira da Silva Airoldi,
  • Felix G. R. Reyes

DOI
https://doi.org/10.1590/S0100-40422008000500048
Journal volume & issue
Vol. 31, no. 5
pp. 1190 – 1198

Abstract

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Different agencies that supply validation guidelines worldwide establish almost the same parameters to be evaluated in the validation process of bioanalytical methods. However, they recommend different procedures, as well as establish different acceptance criteria. The present review delineates and discusses the stages involved in the validation procedures of bioanalytical methods designed for determining veterinary residues in food, explaining the main differences in the guidelines established for this purpose by the main regulatory agencies in the world.

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