Comparison Of Injection Vitamin B12 With Symptomatic Management in Clinically Suspected Vitamin B12 Deficient Patients: An Interventional Study

Abstract

Objectives: This study was an attempt to evaluate the advantage of empirical use of Injection. Vitamin B 12 versus symptomatic management in clinically suspected Vitamin. B 12 deficient patients. Methodology: A total of 100 patients over 20 years of age (irrespective of gender) were included in the study. The patients were divided into two groups, one group ( n = 50) receiving vitamin B12 injections and the other group (n = 50) received symptomatic treatment. Results: In clinically suspected vitamin B12 deficient patients after giving empirical therapy of Inj. Vit B 12; generalized fatigue (96%), pareshtesia (93.48%), myalgia (93.75%), loss of appetite (88.89%), confusion (93.75%) and tremor (93.55%) were improved with ( p<0.001). Labored breathing and depression were also improved with Inj.Vit B 12 as compared to symptomatic management, but this difference was statistically insignificant(p = 0.052 and p = 0.201 respectively). Conclusion: We conclude and recommend from the study to treat clinically suspected Vit. B 12 deficient patients with empirical Vit. B 12 Injections without the need of costly serum Vit. B 12 estimation.

Keywords

• Injection Vit. B 12
• Symptomatic management