Identification of a transcription factor, PunR, that regulates the purine and purine nucleoside transporter punC in E. coli

Irina A. Rodionova; Ye Gao; Anand Sastry; Ying Hefner; Hyun Gyu Lim; Dmitry A. Rodionov; Milton H. Saier; Bernhard O. Palsson

doi:10.1038/s42003-021-02516-0

Communications Biology (Aug 2021)

Identification of a transcription factor, PunR, that regulates the purine and purine nucleoside transporter punC in E. coli

Irina A. Rodionova,
Ye Gao,
Anand Sastry,
Ying Hefner,
Hyun Gyu Lim,
Dmitry A. Rodionov,
Milton H. Saier,
Bernhard O. Palsson

Affiliations

Irina A. Rodionova: Department of Bioengineering, University of California at San Diego
Ye Gao: Department of Bioengineering, University of California at San Diego
Anand Sastry: Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego
Ying Hefner: Department of Bioengineering, University of California at San Diego
Hyun Gyu Lim: Department of Bioengineering, University of California at San Diego
Dmitry A. Rodionov: Sanford-Burnham-Prebys Medical Discovery Institute
Milton H. Saier: Department of Molecular Biology, Division of Biological Sciences, University of California at San Diego
Bernhard O. Palsson: Department of Bioengineering, University of California at San Diego

DOI: https://doi.org/10.1038/s42003-021-02516-0
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 10

Abstract

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Rodionova et al. find that the putative transporter gene, ydhC and its regulator ydhB are involved in purine transportation and that the expression of the ydhC gene is activated by the YdhB in E. coli. The authors suggest renaming the regulator PunR and the transporter PunC, respectively.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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