Sub-nanowatt microfluidic single-cell calorimetry

Sahngki Hong; Edward Dechaumphai; Courtney R. Green; Ratneshwar Lal; Anne N. Murphy; Christian M. Metallo; Renkun Chen

doi:10.1038/s41467-020-16697-5

Nature Communications (Jun 2020)

Sub-nanowatt microfluidic single-cell calorimetry

Sahngki Hong,
Edward Dechaumphai,
Courtney R. Green,
Ratneshwar Lal,
Anne N. Murphy,
Christian M. Metallo,
Renkun Chen

Affiliations

Sahngki Hong: Materials Science and Engineering Program, University of California San Diego
Edward Dechaumphai: Department of Mechanical and Aerospace Engineering, University of California San Diego
Courtney R. Green: Department of Bioengineering, University of California San Diego
Ratneshwar Lal: Materials Science and Engineering Program, University of California San Diego
Anne N. Murphy: Department of Pharmacology, University of California San Diego
Christian M. Metallo: Department of Bioengineering, University of California San Diego
Renkun Chen: Materials Science and Engineering Program, University of California San Diego

DOI: https://doi.org/10.1038/s41467-020-16697-5
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 9

Abstract

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Calorimetrically measuring the heat of single cells is currently not possible due to the sensitivity of existing calorimeters. Here the authors present on-chip single cell calorimetry, with a sensitivity over ten-fold greater than the current gold-standard.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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