Evaluation of alteration in serum lipid levels in patients with chronic periodontitis postperiodontal therapy

Abstract

Aim: There is growing evidence that periodontitis may affect general health. This study was assigned to explore changes in cholesterol levels following nonsurgical periodontal therapy in patients with chronic periodontitis. Materials and methods: Periodontal parameters and lipid profile (total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides and very low-density lipoprotein) were evaluated in 50 subjects suffering from moderate to severe generalized chronic periodontitis. Results: At third month, there was significant reduction in total cholesterol, low density lipoprotein, very low density lipoprotein, triglyceride and increase in high density lipoprotein after nonsurgical periodontal therapy (NSPT). Also, the reduction in bleeding on probing, pocket depth and attachment level were statistically significant in the treatment group. Conclusion: The results of our study showed that periodontal destruction and serum lipid levels are positively correlated and nonsurgical periodontal treatment in chronic periodontitis patients resulted in significant changes in the concentration of total cholesterol, triglycerides, HDL. LDL levels in blood serum.

Keywords

• Chronic periodontitis
• Cholesterol
• NSPT