Radiology Case Reports (May 2024)

Epipericardial fat necrosis diagnosed by cardiac CT in a patient with apical hypertrophic cardiomyopathy

  • Miyuko Fujita, MD,
  • Kakuya Kitagawa, MD, PhD,
  • Kensuke Domae, MD,
  • Shintaro Yamaguchi, MD,
  • Takanori Kokawa, MD,
  • Masafumi Takafuji, MD, PhD,
  • Yasutaka Ichikawa, MD, PhD,
  • Hajime Sakuma, MD, PhD

Journal volume & issue
Vol. 19, no. 5
pp. 1708 – 1711

Abstract

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Epipericardial fat necrosis (EFN) is a rare benign cause of chest pain, that is frequently overlooked. EFN involves the necrosis of fat tissue in the mediastinum, and presents on computed tomography (CT) as an ovoid lesion of fat attenuation surrounded by a rim of soft tissue attenuation. This case report describes a case of a 50-year-old man diagnosed with EFN on cardiac CT, which was incidentally associated with apical hypertrophic myocardiopathy. Notably, the detection of EFN proved difficult on arterial phase images during coronary CT angiography, whereas it was much easier to detect on delayed phase images. EFN should be considered in the differential diagnosis of chest pain, and careful examination of mediastinal fat is crucial for accurate diagnosis.

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