Synthesis, Characterization and Biological Activity of Some Mixed Ligand Complexes of 1, 10-Phenanthronline and [4-(2-hydroxy-1,2-diphenylethylideneamino)-N-pyrimidin-2-yl) benzene sulfonamide] with Divalent Metal Ions

Abstract

Schiff base ligand [4-(2-hydroxy-1, 2-diphenylethylideneamino)-N-pyrimidin-2-yl)benzene sulfonamide] (L) was prepared through a condensation reaction of sulfadiazine and benzoin in acidic medium. The prepared ligand has been characterized with different techniques (C.H.N.S, FT-IR, UV-Vis and 1H&13C-N.M.R). Mixed ligand complexes of some divalent metal ions [Co(II), Mn(II), Ni(II),Cu(II) and Hg(II)] were prepared by the reaction of [4-(2-hydroxy-1,2-diphenylethylidene amino)-N-pyrimidin-2-yl)benzene sulfonamide](L) and 1,10-Phenanthronline with the metal ions in basic conditions. The prepared complexes were characterized and their astrochemical structures and geometries were suggested depending upon data of (UV-Vis, FT-IR, atomic absorption, micro elemental analysis The following general formula was achieved : [M(PHN)(L)2], where M represent (Co(II)- Cu(II)-Mn(II)- Ni(II) and Hg(II)). Electronic spectra supported by magnetic moment's revealed octahedral geometries for all the prepared complexes. The mixed complexes showed resistivity to different bacteria such as(Pseudomonas aeruginosa), (Bacillus subtilis), (Escherichia coli), and (staphylococcus aureus).

Keywords

• Schiff base, benzoin, Characterization, Mixed ligand complexes.