Nature Communications (Dec 2020)

Integrative modeling of membrane-associated protein assemblies

  • Jorge Roel-Touris,
  • Brian Jiménez-García,
  • Alexandre M. J. J. Bonvin

DOI
https://doi.org/10.1038/s41467-020-20076-5
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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Most approaches for modeling the membrane protein complexes are not capable of incorporating the topological information provided by the membrane. Here authors present an integrative computational protocol for the modeling of membrane-associated protein assemblies, specifically complexes consisting of a membrane-embedded protein and a soluble partner.