The Canonical Long-Chain Fatty Acid Sensing Machinery Processes Arachidonic Acid To Inhibit Virulence in Enterohemorrhagic Escherichia coli

Melissa Ellermann; Angel G. Jimenez; Reed Pifer; Nestor Ruiz; Vanessa Sperandio

doi:10.1128/mBio.03247-20

mBio (Feb 2021)

The Canonical Long-Chain Fatty Acid Sensing Machinery Processes Arachidonic Acid To Inhibit Virulence in Enterohemorrhagic Escherichia coli

Melissa Ellermann,
Angel G. Jimenez,
Reed Pifer,
Nestor Ruiz,
Vanessa Sperandio

Affiliations

Melissa Ellermann: Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Angel G. Jimenez: Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Reed Pifer: Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Nestor Ruiz: Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Vanessa Sperandio: ORCiD; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

DOI: https://doi.org/10.1128/mBio.03247-20
Journal volume & issue: Vol. 12, no. 1

Abstract

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Polyunsaturated fatty acids (PUFAs) play important roles in host immunity. Manipulation of lipid content in host tissues through diet or pharmacological interventions is associated with altered severity of various inflammatory diseases.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal