Doxazosin Effect on Neurogenic Bladder with Urine Retention in Female Dogs

Abstract

Abstract: This short communication describes the effect of Doxazosin in case of urinary retention in female dogs due to motor neuron lesions produced by spinal trauma or spinal compression consecutively to intervertebral disk degeneration and extrusion. The study aims to determine whether the treatment of urinary retention in case of neurogenic bladder in female dogs, using 1 adrenergic blocker is effective in spontaneous recovery of the examined patients. Ten female dogs presenting with urinary retention were examined in the laboratory of Radiology, Faculty of Veterinary Medicine Cluj Napoca. The patients were examined using CT, radiography and ultrasonography in order to identify the spinal cord injury that is responsible for neurogenic bladder. The dose of Doxazosin used in treatment of voiding problem in neurogenic bladder was 1mg/kg, single dose per day. Depending on the spinal cord compression cause, the urine retention symptom was resolved.

Keywords

• α1-adrenergic blocking agent
• α adrenoreceptor
• neurogenic bladder