Lipid profile of Hyperlipidemic mice induced by dexamethasone treated with 105 herbals oil mixture

Abstract

Background: Lipid profile is a panel of blood tests that serves as an initial broad medical screening tool for abnormalities in lipids, such as cholesterol and triglycerides. Objective: This study estimates the activity of mixture of three herbal seed oil on the lipid profile of hyperlipidemic mice induced by glucocorticoid drug.This mixture 105 composed of: 30% Petroselinumcrispum, 35% Lepidiumsativumand 35% Eruca sativa seed oil. Patients and Methods: The study was conductedusing 30 Swiss albino mice of 4 weeks age, which were divided into three equal groups. First group treated with dexamethasone drug, the second group treated with dexamethasone plus oil mixture,while the third group served as control. Results: It showed that the mixture [105] had the activity to decrease the lipid profile of hyperlipidemic mice induced by dexamethasone after treatment with 7,14, 21 days. Conclusion: Petroselinumcrispum, Lepidiumsativumand Eruca sativa seed oil have activity to decrease the levels of lipid profile in dexamethasone –induced hyperlipidemia mice.

Keywords

• Petroselinumcrispum, Lepidiumsativum ,Eruca sativa, seed oil, Dexamethasone herbal oil