ACS Central Science (Oct 2017)
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity
- Frederick M. Tomlin,
- Ulla I. M. Gerling-Driessen,
- Yi-Chang Liu,
- Ryan A. Flynn,
- Janakiram R. Vangala,
- Christian S. Lentz,
- Sandra Clauder-Muenster,
- Petra Jakob,
- William F. Mueller,
- Diana Ordoñez-Rueda,
- Malte Paulsen,
- Naoko Matsui,
- Deirdre Foley,
- Agnes Rafalko,
- Tadashi Suzuki,
- Matthew Bogyo,
- Lars M. Steinmetz,
- Senthil K. Radhakrishnan,
- Carolyn R. Bertozzi
Affiliations
- Frederick M. Tomlin
- Department of Chemistry, Stanford University, Stanford, California, United States
- Ulla I. M. Gerling-Driessen
- Department of Chemistry, Stanford University, Stanford, California, United States
- Yi-Chang Liu
- Department of Chemistry, Stanford University, Stanford, California, United States
- Ryan A. Flynn
- Department of Chemistry, Stanford University, Stanford, California, United States
- Janakiram R. Vangala
- Department of Pathology, Virginia Commonwealth University, Richmond, Virginia, United States
- Christian S. Lentz
- Department of Pathology, Stanford University School of Medicine, Stanford, California, United States
- Sandra Clauder-Muenster
- Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
- Petra Jakob
- Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
- William F. Mueller
- Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
- Diana Ordoñez-Rueda
- Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
- Malte Paulsen
- Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
- Naoko Matsui
- Glycomine, Inc., San Francisco, California, United States
- Deirdre Foley
- Glycomine, Inc., San Francisco, California, United States
- Agnes Rafalko
- Glycomine, Inc., San Francisco, California, United States
- Tadashi Suzuki
- Glycometabolome Team, Systems Glycobiology Research Group, RIKEN Global Research Cluster, Wako, Saitama, Japan
- Matthew Bogyo
- Department of Pathology, Stanford University School of Medicine, Stanford, California, United States
- Lars M. Steinmetz
- Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
- Senthil K. Radhakrishnan
- Department of Pathology, Virginia Commonwealth University, Richmond, Virginia, United States
- Carolyn R. Bertozzi
- Department of Chemistry, Stanford University, Stanford, California, United States
- DOI
- https://doi.org/10.1021/acscentsci.7b00224
- Journal volume & issue
-
Vol. 3,
no. 11
pp. 1143 – 1155
Abstract
No abstracts available.