Acta Biomedica Scientifica (Apr 2013)
Heart rate variability and structural and functional disorders of myocardium in patients with chronic prostatitis
Abstract
The aim. of work was to study the relationship between structural and functional changes in the myocardium and the parameters of heart rate variability in patients with chronic prostatitis. The study included 51 patient with chronic prostatitis of average age 34,2 ± 8,1 years. The study excluded patients older than 45 years, with various heart diseases, arterial hypertension and a history of inflammatory diseases of any other localization. Echocardiography research was carried out by standard methods on the device "VIVID-3-expert GE". All the patients had. Holter ECG monitoring with analysis of heart rate variability. In patients with chronic prostatitis the disorder of vegetative cardiovascular regulation of cardiac activity in the form of hypersympathotony and. significant reduction of protective vagal activity was revealed. Main differences of structural and. functional parameters of myocardium related to such indices as the thickness of the posterior wall, interventricular septum, left ventricular myocardial mass, time, isovolumetric relaxation of the left ventricle, which in patients with diastolic dysfunction of the left ventricle and. left atrium dilatation significantly higher than those settings intact myocardium of the left ventricle and. atrium, as well as a control group. The lowest values of heart rate variability reported in patients with structural and. functional changes in the myocardium of the left atrium and. diastolic dysfunction of the left ventricular. Thus, one of the mechanisms of left ventricular remodeling in patients with chronic prostatitis, a vegetative imbalance with sympathotony associated with lower basic spectral, temporal and geometry of heart rate variability. Prolonged activation of the sympathetic nervous system autonomic managers may directly or indirectly (through the renin-angiotensin-aldosterone system) to initiate and. maintain the processes of excessive growth of cardiomyocytes, contributing to dysfunction of left ventricular relaxation, in patients with chronic prostatitis
