Teknik Lem Fibrin Otologus pada Cangkok Konjungtiva Bulbi Mata Kelinci

Abstract

Commercial Fibrin Glue (CFG) as a biomaterial adhesive from fresh frozen plasma donor and bovine has been tested having various superiorities compared to suturing in bulbar conjunctiva grafting of pterygium surgery. Due to CFG has not been available in Indonesia led the author to make an Autologous Fibrin Glue (AFG) directly from patient's own blood. The study aim was to investigate the effectiveness of AFG attachment. This study was an animal experimental, conducted in 24 New Zealand White rabbits divided into AFG group and suturing group of 12 rabbits each, held in Laboratory of Bio Farma, Bandung, from September to December 2006. The assessment included duration (in minute) of AFG compared to suturing techniques, also at first day and one week post grafting attachments in bulbar conjunctiva grafting. The statistical analysis used Mann-Whitney and Wilcoxon rank test. In time duration of surgical treatment, AFG technique was significantly shorter than suturing technique (p=0.0001), while first day and one week post grafting AFG attachment showed significantly greater than those of suturing attachment (p=0.0001). In the meantime, first day and one week post grafting AFG attachment was steady state, whereas in suturing technique was different (p=0.0174). In conclusion, AFG technique is more effective than suturing technique in bulbar conjunctiva grafting because of shorter surgical duration, excellent and stable graft attachment.

Keywords

• Autologous fibrin glue
• suturing technique
• fresh frozen plasma
• bulbar conjunctival grafting