Unveiling metabolic flux changes during acute cold exposure

Abstract

Controlling energy expenditure during acute cold exposure is a fundamental aspect of metabolic dynamics in organisms. However, prior studies on cold-induced thermogenesis faced limitations, primarily focusing on brown adipose tissue (BAT) and lacking precise in vivo flux measurements. This editorial aims to highlight the recent research by Bornstein et al. providing a comprehensive and quantitative insight into the intricate alterations in metabolic flux that drive this phenomenon[1].