Cytotoxicity of Silver Nanoparticles Synthesized With the Assistant of Microwave

Abstract

Silver nanoparticles (AgNPs) are broadly designed for various application. In the current research silver nanoparticles (AgNPs) have been examined for their poisonous outcome on human lymphocyte and chicken embryo fibroblast cell line. AgNPs were synthesized by a simple and easy method from AgNO3 solution with glucose exposed to microwave radiation. The typical size of AgNPs were 30 nm with spherical shape. The cells which cultured with diverse concentrations of silver were examined for their viability using MTT assess, a photometric technique to conclude cell metabolism. The results show that the cell viability of the both cell type were diminished significantly (P<0.05) in dosage dependent mode, and the silver nanoparticles presented higher cytotoxicity to CEF than to human lymphocyte at the same concentration and time point.

Keywords

• silver nanoparticles
• cytotoxic
• nanotechnology
• microwave assisted