Collagen vs expanded polytetrafluorethylene membranes during guided-bone regeneration simultaneous with implant placement – a systematic review

Abstract

Purpose: This systematic review evaluated the influence of the membrane type (resorbable collagen or non-resorbable expanded polytetrafluorethylene; e-PTFE) on the guided-bone regeneration associated to implant placement. Methods: Any type of clinical study or literature review was searched at MEDLINE/PubMed and Cochrane databases. Two independent reviewers screened titles/abstracts of articles and the full-text of potentially eligible studies. When data was available, pairwise meta-analysis was performed using random statistical model. Results: Nine studies met the inclusion criteria, considering 685 implants in 360 patients. Vertical bone regeneration did not differ with the use of the two membranes in 8 of the 9 studies included. Meta-analysis did not show either greater vertical bone gain or vertical bone loss after regeneration with any of the membranes. The results have shown a tendency of higher bone gain in horizontal guided-bone regeneration with non-resorbable e-PTFE membranes (reported by 2 of 3 studies). All studies clearly showed that both membranes were effective in increase bone volume. There was no clear tendency of any of the two membranes in cause more complications. Conclusion: resorbable collagen and non-resorbable e-PTFE membranes are similarly effective in vertical guided-bone regeneration; however, horizontal guided-bone regeneration seems to benefit with the use of non-resorbable ones. Both membranes showed to be effective in guided-bone regeneration and similar in regards to complications.

Keywords

• dental implants
• vertical bone gain
• horizontal bone gain