Generation of Mouse Spinal Cord Injury

Oneil Bhalala; Liuliu  Pan; Hilary  North; Tammy  McGuire; John Kessler

doi:10.21769/BioProtoc.886

Bio-Protocol (Sep 2013)

Generation of Mouse Spinal Cord Injury

Oneil Bhalala,
Liuliu Pan,
Hilary North,
Tammy McGuire,
John Kessler

Affiliations

Oneil Bhalala: Department of Neurology, Northwestern University, Chicago, USA
Liuliu Pan: Department of Neurology, Northwestern University, Chicago, USA
Hilary North: Department of Neurology, Northwestern University, Chicago, USA
Tammy McGuire: Department of Neurology, Northwestern University, Chicago, USA
John Kessler: Department of Neurology, Northwestern University, Chicago, USA

DOI: https://doi.org/10.21769/BioProtoc.886
Journal volume & issue: Vol. 3, no. 17

Abstract

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Spinal cord injury (SCI) is a debilitating injury with significant morbidity and mortalitiy. Understanding the pathogensis of and developing treatments for SCI requires robust animal models. Here we describe a method for generating an efficient and reproducible contusion model of SCI in adult mice.

Published in Bio-Protocol

ISSN: 2331-8325 (Online)
Publisher: Bio-protocol LLC
Country of publisher: United States
LCC subjects: Science: Biology (General)
Website: https://bio-protocol.org

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