Nature Communications (Dec 2017)

Input-dependent regulation of excitability controls dendritic maturation in somatosensory thalamocortical neurons

  • Laura Frangeul,
  • Vassilis Kehayas,
  • Jose V. Sanchez-Mut,
  • Sabine Fièvre,
  • K. Krishna-K,
  • Gabrielle Pouchelon,
  • Ludovic Telley,
  • Camilla Bellone,
  • Anthony Holtmaat,
  • Johannes Gräff,
  • Jeffrey D. Macklis,
  • Denis Jabaudon

DOI
https://doi.org/10.1038/s41467-017-02172-1
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 10

Abstract

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Sensory input and neuronal activity are crucial for proper morphological development of neurons. Here, Frangeul and colleagues show that membrane excitability is a critical component of dendritic development in mouse somatosensory thalamocortical neurons.