Isatinones A and B, New Antifungal Oxindole Alkaloids from Isatis costata

Abstract

Two new oxindole alkaloids isatinone A (1) and B (2) have been isolated from Isatis costata, along with the known trisindoline. Their structures have been assigned on the basis of spectroscopic techniques and chemical studies. Both new compounds showed significant antifungal activity.

Keywords

• Isatis costata
• Brassicaseae
• oxindole alkaloids
• structure elucidation
• antifungal activity