Atividade biológica do lapachol e de alguns derivados sobre o desenvolvimento fúngico e em germinação de sementes Biological activity of lapachol and some derivatives as antifungal and in seed germination

Abstract

The natural quinones lapachol, α-lapachone and β-lapachone, and the synthetic derivative β-lapachone-3-sulfonic-acid were assayed for inhibition of fungal growth (Fusarium oxysporum) and germination of lettuce seeds (Lactuca sativa L.). β-Lapachone has the strongest activity as a germination inhibitor and lapachol shows no effect. β-Lapachone, followed by lapachol, are the most active in reducing fungal growth.

Keywords

• lapachol
• Fusarium oxysporum
• Lactuca sativa L