International Medical Case Reports Journal (Jan 2020)
Primary Osteosarcoma of the Breast with Extensive Chondroid Matrix in a Teenager Female Patient: The Paradoxical Diagnosis in Breast Mastopathy
Abstract
James Joseph Yahaya, 1, 2 Michael Odida 1 1Department of Pathology, Makerere College of Health Sciences (MakCHS), Kampala, Uganda; 2Department of Biomedical Sciences, College of Health Sciences (CHS), the University of Dodoma, Dodoma, TanzaniaCorrespondence: James Joseph YahayaDepartment of Pathology, Makerere College of Health Sciences (MakCHS), P.O. Box 7072, Kampala, UgandaTel +256 784 847 139Email [email protected]: Non-epithelial tumors of the breast are extremely rare and have an incidence of less than 1%. The most common non-epithelial breast tumor is the phyllodes tumor (PT), which accounts for 61%. Primary osteosarcomas of the breast contribute up to only 12.5% of all breast sarcomas. In young females, osteosarcomas are extremely rare, especially in those without a previous history of primary bone osteosarcoma. A case of a 16-year old female with primary osteosarcoma of the breast (POB) with extensive chondroid matrix involving the left breast is herein presented.Case Report: This report describes a 16-year old female with neither a previous history of bone osteosarcoma nor family history of breast cancer who was diagnosed with a primary chondroblastic osteosarcoma of the left breast. The mass was shining, warm, firm, and slightly fixed. The excisional biopsy showed a large tumor measuring 11x9x7 cm which was encapsulated, grayish-white, and nodular.Conclusion: Primary osteosarcomas of the breast carry a poor prognosis by being triple negative and because of being the rarest tumors, they pose a challenge in managing the patients due to lack of established treatment modalities.Keywords: osteosarcoma, breast, triple negative
