Veno-venous Extracorporeal Membrane Oxygenation in a case of organophosphorus poisoning

Abstract

Extracorporeal Membrane Oxygenation (ECMO) is emergently used for long-term support of respiratory and/or cardiac functions. ECMO is most useful in cases when the primary lung insult is reversible. CESAR trial in 2009 showed survival benefits in severe ARDS patients when transferred to an ECMO center compared to those receiving standard care in their ICU. Organophosphate (OP) compounds are large groups of chemicals used in domestic and industrial settings. These compounds are still used in different forms in developing countries. It can affect the respiratory system through causing: rhinorrhea, bronchorrhea, bronchospasm, cough and severe respiratory distress. Respiratory failure is the most life threatening condition and requires immediate intervention. We present a case report of OP induced severe ARDS in which conventional lung protective ventilation failed to maintain adequate oxygenation that was accomplished by ECMO.

Keywords

• ECMO
• Severe ARDS
• Organophosphorus poisoning