Analysis of Causative Factors in Oral Cancer

Abstract

Objective: To analyse different causative factors leading to oral cancer. Study Design: Descriptive type of study.Setting: This study was conducted at the department of E.N.T, DUHS, Karachi. Study Period: From Jan 2008, to October 2008. Subjects & Methods: Fifty histopathologically proven patients of oral cancer were selected andanalyzed regarding predisposing and causative factors. Patients having premalignant oral disease, postoperative, post radiotherapy patients and patients with inconclusive reports ofhistopathology were notincluded in this study. Results: The analyses of 50 cases of oral cancer revealed that the majority of the patients were indulgedin the habit of Paan, Betel nut, Naswar, Tobacco Chewing and smoking. 42 out of 50 patients (84%)had history of indulgence into these habits. Only eight out of 50 cases (16%) had no habit of Pan, Betelnut, Naswar and smoking. Early tertiary care hospital presentation was only 36% and patients presentedwith stage II or I. Sixty four percent (64%) patients who reported at Civil Hospital Karachi (CHK) hadstage III or IV. Conclusion: The analysis of fifty patients of oral cancer revealed that majority of the patients wereindulged in different chewing and smoking habits. Betel nut, Tobacco, Naswar and Paan Chewing weredifferent causative and predisposing factors of oral cancer.