Agrology (Oct 2023)
The effect of methionin, phenaron, and metiphen in different doses on the activity of the enzymatic link of the antioxidant protection of the piglets’ bodies
Abstract
Abstract. Peroxidation of all lipids in the body is controlled by the system of antioxidant protection, which ensures the binding and modification of free radicals, preventing the formation or destruction of peroxides. We studied the effects of methionin, phenaron, and metiphen in appropriate doses on the activity of the enzymatic link of the antioxidant protection of the piglets' bodies. The research was conducted on 50 three-month-old piglets of the Large White Breed. The diet of the piglets was balanced in terms of nutrients and minerals. Based on the experimental studies, the correcting effect of methionin, phenaron, and metiphen on the activity of enzymes in the antioxidant defense system has been scientifically proven. In the piglets, the experimental drugs helped to increase the enzymatic link of the system of antioxidant protection: increase in the activity of superoxide dismutase, catalase, and glutathione peroxidase in the blood serum of the studied piglets. The highest indicators of the activity of the specified enzymes in the blood serum of the animals of the experimental groups were seen on the 30th, 60th, and 90th days of the experiment. It is worth noting that the experimental drugs showed better antioxidant properties in the appropriate doses: methionin at the dose of 4 mg/kg of body weight and phenaron at the dose of 1.20 mg/kg body weight. And metifen at the dose of 0.9 mg/kg of body weight. The use of methiphen in piglets contributed to a better antioxidant effect than phenaron and methionin separately. The components of metiphen act as synergists; therefore, they better strengthened the antioxidant protection of the piglets' bodies
