Methotrexate-induced lung damage in a patient with rheumatoid arthritis

Abstract

We herein report a case of interstitial lung disease secondary to the use of methotrexate in a patient with rheumatoid arthritis. Differential diagnosis between pneumonitis caused by methotrexate in patients treated with basic methotrexate therapy and interstitial pulmonary disease associated with rheumatoid arthritis is based on the clinical examination and instrumental data. The main condition for favorable clinical outcome in all drug-induced lung disease is drug withdrawal, what was proven in our report.

Keywords

• methotrexate
• rheumatoid arthritis
• pulmonary fibrosis
• drug-induced lung disease