Nature Communications (Mar 2021)
A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution
- Wesley C. Warren,
- Tyler E. Boggs,
- Richard Borowsky,
- Brian M. Carlson,
- Estephany Ferrufino,
- Joshua B. Gross,
- LaDeana Hillier,
- Zhilian Hu,
- Alex C. Keene,
- Alexander Kenzior,
- Johanna E. Kowalko,
- Chad Tomlinson,
- Milinn Kremitzki,
- Madeleine E. Lemieux,
- Tina Graves-Lindsay,
- Suzanne E. McGaugh,
- Jeffrey T. Miller,
- Mathilda T. M. Mommersteeg,
- Rachel L. Moran,
- Robert Peuß,
- Edward S. Rice,
- Misty R. Riddle,
- Itzel Sifuentes-Romero,
- Bethany A. Stanhope,
- Clifford J. Tabin,
- Sunishka Thakur,
- Yoshiyuki Yamamoto,
- Nicolas Rohner
Affiliations
- Wesley C. Warren
- Department of Animal Sciences, Institute for Data Science and Informatics, Bond Life Sciences Center, University of Missouri
- Tyler E. Boggs
- Department of Biological Sciences, University of Cincinnati
- Richard Borowsky
- Department of Biology, New York University
- Brian M. Carlson
- Department of Biological Sciences, Northern Kentucky University
- Estephany Ferrufino
- Harriet L. Wilkes Honors College, Florida Atlantic University
- Joshua B. Gross
- Department of Biological Sciences, University of Cincinnati
- LaDeana Hillier
- Department of Genome Sciences, University of Washington
- Zhilian Hu
- Department of Physiology, Anatomy and Genetics, University of Oxford
- Alex C. Keene
- Department of Biological Sciences, Florida Atlantic University
- Alexander Kenzior
- Stowers Institute for Medical Research
- Johanna E. Kowalko
- Harriet L. Wilkes Honors College, Florida Atlantic University
- Chad Tomlinson
- McDonnell Genome Institute, Washington University
- Milinn Kremitzki
- McDonnell Genome Institute, Washington University
- Madeleine E. Lemieux
- Bioinfo
- Tina Graves-Lindsay
- McDonnell Genome Institute, Washington University
- Suzanne E. McGaugh
- Department of Ecology, Evolution, and Behavior, University of Minnesota
- Jeffrey T. Miller
- Department of Ecology, Evolution, and Behavior, University of Minnesota
- Mathilda T. M. Mommersteeg
- Department of Physiology, Anatomy and Genetics, University of Oxford
- Rachel L. Moran
- Department of Ecology, Evolution, and Behavior, University of Minnesota
- Robert Peuß
- Stowers Institute for Medical Research
- Edward S. Rice
- Bond Life Sciences Center, University of Missouri
- Misty R. Riddle
- Genetics Department, Blavatnik Institute, Harvard Medical School
- Itzel Sifuentes-Romero
- Harriet L. Wilkes Honors College, Florida Atlantic University
- Bethany A. Stanhope
- Harriet L. Wilkes Honors College, Florida Atlantic University
- Clifford J. Tabin
- Genetics Department, Blavatnik Institute, Harvard Medical School
- Sunishka Thakur
- Harriet L. Wilkes Honors College, Florida Atlantic University
- Yoshiyuki Yamamoto
- Department of Cell and Developmental Biology, University College London
- Nicolas Rohner
- Stowers Institute for Medical Research
- DOI
- https://doi.org/10.1038/s41467-021-21733-z
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 12
Abstract
Mexican Tetra cavefish have long been of interest in understanding adaptation to severe environmental change. Here the authors present a chromosome-level genome for the proxy-ancestral surface fish, and use CRISPR gene-editing to show the role of the rx3 gene in eye size.
