Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds

Takashi Yamazaki; Yoh Nakajima; Minato Iida; Tomoko Kawasaki-Takasuka

doi:10.3762/bjoc.17.14

Beilstein Journal of Organic Chemistry (Jan 2021)

Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds

Takashi Yamazaki,
Yoh Nakajima,
Minato Iida,
Tomoko Kawasaki-Takasuka

Affiliations

Takashi Yamazaki: Division of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei 184-8588, Japan
Yoh Nakajima: Division of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei 184-8588, Japan
Minato Iida: Division of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei 184-8588, Japan
Tomoko Kawasaki-Takasuka: Division of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei 184-8588, Japan

DOI: https://doi.org/10.3762/bjoc.17.14
Journal volume & issue: Vol. 17, no. 1
pp. 132 – 138

Abstract

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The concise preparation of 4,4,4-trifluorobut-2-yn-1-ones by the oxidation of the readily accessible corresponding propargylic alcohols as well as their utilization as Michael acceptors for the construction of aromatic and heteroaromatic compounds are reported.

Published in Beilstein Journal of Organic Chemistry

ISSN: 1860-5397 (Online)
Publisher: Beilstein-Institut
Country of publisher: Germany
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.beilstein-journals.org/bjoc

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