The Effects of Postoperative Trimetazidine Treatment on Ischemia-Reperfusion Injury after Isolated Surgical Myocardial Revascularization

Abstract

Surgical revascularization is the gold standard in the management of patients with multi-vessel coronary artery disease (CAD). It is well known that increased oxidative stress during ischemia-reperfusion and post-revascularization procedures leads to the release of free radical in the circulation. This process can cause reversible or irreversible myocardial damage.

Keywords

• trimetazidine
• malondialdehyde
• oxidative stress
• coronary artery bypass grafting
• postoperative results