mBio (Apr 2021)
Analysis of the Long-Term Impact on Cellular Immunity in COVID-19-Recovered Individuals Reveals a Profound NKT Cell Impairment
- Jia Liu,
- Xuecheng Yang,
- Hua Wang,
- Ziwei Li,
- Hui Deng,
- Jing Liu,
- Shue Xiong,
- Junyi He,
- Xuemei Feng,
- Chunxia Guo,
- Weixian Wang,
- Gennadiy Zelinskyy,
- Mirko Trilling,
- Kathrin Sutter,
- Tina Senff,
- Christopher Menne,
- Joerg Timm,
- Yanfang Zhang,
- Fei Deng,
- Yinping Lu,
- Jun Wu,
- Mengji Lu,
- Dongliang Yang,
- Ulf Dittmer,
- Baoju Wang,
- Xin Zheng
Affiliations
- Jia Liu
- ORCiD
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Xuecheng Yang
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Hua Wang
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Ziwei Li
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Hui Deng
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Jing Liu
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Shue Xiong
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Junyi He
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Xuemei Feng
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Chunxia Guo
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Weixian Wang
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Gennadiy Zelinskyy
- Institute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany
- Mirko Trilling
- ORCiD
- Institute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany
- Kathrin Sutter
- Institute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany
- Tina Senff
- Institute for Virology, Heinrich-Heine-University, University Hospital, Duesseldorf, Germany
- Christopher Menne
- Institute for Virology, Heinrich-Heine-University, University Hospital, Duesseldorf, Germany
- Joerg Timm
- Institute for Virology, Heinrich-Heine-University, University Hospital, Duesseldorf, Germany
- Yanfang Zhang
- Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
- Fei Deng
- ORCiD
- Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
- Yinping Lu
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Jun Wu
- ORCiD
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Mengji Lu
- Institute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany
- Dongliang Yang
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Ulf Dittmer
- Institute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany
- Baoju Wang
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Xin Zheng
- Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- DOI
- https://doi.org/10.1128/mBio.00085-21
- Journal volume & issue
-
Vol. 12,
no. 2
Abstract
Wuhan was the very first city hit by SARS-CoV-2. Accordingly, the patients who experienced the longest phase of convalescence following COVID-19 reside here.