Nature Communications (Mar 2019)
Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage
- Rene S. Hendriksen,
- Patrick Munk,
- Patrick Njage,
- Bram van Bunnik,
- Luke McNally,
- Oksana Lukjancenko,
- Timo Röder,
- David Nieuwenhuijse,
- Susanne Karlsmose Pedersen,
- Jette Kjeldgaard,
- Rolf S. Kaas,
- Philip Thomas Lanken Conradsen Clausen,
- Josef Korbinian Vogt,
- Pimlapas Leekitcharoenphon,
- Milou G. M. van de Schans,
- Tina Zuidema,
- Ana Maria de Roda Husman,
- Simon Rasmussen,
- Bent Petersen,
- The Global Sewage Surveillance project consortium,
- Clara Amid,
- Guy Cochrane,
- Thomas Sicheritz-Ponten,
- Heike Schmitt,
- Jorge Raul Matheu Alvarez,
- Awa Aidara-Kane,
- Sünje J. Pamp,
- Ole Lund,
- Tine Hald,
- Mark Woolhouse,
- Marion P. Koopmans,
- Håkan Vigre,
- Thomas Nordahl Petersen,
- Frank M. Aarestrup
Affiliations
- Rene S. Hendriksen
- National Food Institute, Technical University of Denmark
- Patrick Munk
- National Food Institute, Technical University of Denmark
- Patrick Njage
- National Food Institute, Technical University of Denmark
- Bram van Bunnik
- Usher Institute, University of Edinburgh
- Luke McNally
- Centre for Synthetic and Systems Biology, School of Biological Sciences, University of Edinburgh
- Oksana Lukjancenko
- National Food Institute, Technical University of Denmark
- Timo Röder
- National Food Institute, Technical University of Denmark
- David Nieuwenhuijse
- Viroscience, Erasmus Medical Center
- Susanne Karlsmose Pedersen
- National Food Institute, Technical University of Denmark
- Jette Kjeldgaard
- National Food Institute, Technical University of Denmark
- Rolf S. Kaas
- National Food Institute, Technical University of Denmark
- Philip Thomas Lanken Conradsen Clausen
- National Food Institute, Technical University of Denmark
- Josef Korbinian Vogt
- National Food Institute, Technical University of Denmark
- Pimlapas Leekitcharoenphon
- National Food Institute, Technical University of Denmark
- Milou G. M. van de Schans
- RIKILT Wageningen University and Research
- Tina Zuidema
- RIKILT Wageningen University and Research
- Ana Maria de Roda Husman
- National Institute for Public Health and the Environment (RIVM)
- Simon Rasmussen
- Department of Bio and Health Informatics, Technical University of Denmark
- Bent Petersen
- Department of Bio and Health Informatics, Technical University of Denmark
- The Global Sewage Surveillance project consortium
- Clara Amid
- European Molecular Biology Laboratory, European Bioinformatics Institute
- Guy Cochrane
- European Molecular Biology Laboratory, European Bioinformatics Institute
- Thomas Sicheritz-Ponten
- Centre of Excellence for Omics-Driven Computational Biodiscovery, AIMST University
- Heike Schmitt
- National Institute for Public Health and the Environment (RIVM)
- Jorge Raul Matheu Alvarez
- World Health Organization
- Awa Aidara-Kane
- World Health Organization
- Sünje J. Pamp
- National Food Institute, Technical University of Denmark
- Ole Lund
- Department of Bio and Health Informatics, Technical University of Denmark
- Tine Hald
- National Food Institute, Technical University of Denmark
- Mark Woolhouse
- Usher Institute, University of Edinburgh
- Marion P. Koopmans
- Viroscience, Erasmus Medical Center
- Håkan Vigre
- National Food Institute, Technical University of Denmark
- Thomas Nordahl Petersen
- National Food Institute, Technical University of Denmark
- Frank M. Aarestrup
- National Food Institute, Technical University of Denmark
- DOI
- https://doi.org/10.1038/s41467-019-08853-3
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 12
Abstract
Obtaining data on antimicrobial resistance (AMR) from healthy human populations is difficult. Here, Hendriksen et al. use metagenomic analysis to obtain AMR data from untreated sewage from 79 sites in 60 countries, finding correlations with socio-economic, health and environmental factors.
