Can we cure type 1 diabetes?

Abstract

Last year we celebrated the centenary of the discovery of insulin, which occurred at the University of Toronto, Canada, thanks to the research work of Frederick Banting and Charles Best, with the collaboration of James Collip and John Macleod. Such was the impact that in 1923, Banting and Mcleod were awarded the Nobel Prize for Medicine. Since then, exogenous insulin has been the main hormone replacement therapy in insulin-dependent or insulin-requiring patients. Although this treatment works successfully in most patients, there is a group that does not achieve adequate metabolic goals and is exposed to episodes of hyperglycemia or hypoglycemia, which in the long term determine the appearance of secondary complications of diabetes or cause decompensation and death.

Keywords

• diabetes mellitus
• insulina